The NIH Blueprint for Neuroscience Research is a collaborative framework between the NIH Office of the Director and 12 NIH Institutes and Centers (ICs) to support research on the nervous system. By pooling resources and expertise, the Blueprint identifies cross-cutting areas of research and confronts challenges too large for any single IC. The NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP-ENDURE) aims to raise interest and opportunities in neuroscience research for individuals who are typically underrepresented in the neurosciences. The goal is to provide such individuals with training at the undergraduate level, so that they are prepared to enter and successfully complete neuroscience PhD programs. ENDURE provides undergraduate training through partnerships between research-intensive institutions and institutions with a substantial enrollment of neuroscience majors from diverse groups. This includes individuals from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from economically disadvantaged backgrounds. ENDURE undergraduate training programs support a range of activities to increase student interest and involvement in the neurosciences, including research experiences, core and advanced neuroscience courses, seminars, and journal clubs. In FY10, five ENDURE awards were granted and six awards were granted in FY15. We currently have ten active awards, with six awards made in FY20 and four in FY21.